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Profile Detail

Min-Ho Kim

Assistant Professor

Postdoc research in Biomedical Engineering at University of California-Davis

Ph.D in Bioengineering at Pennsylvania State University

Scholarly, Creative & Professional Activities

Research Interests

The major focus of my research interest is to develop therapeutics to promote the resolution of non-healing chronic wounds based on precise understanding of inflammatory response to tissue injury and infection.Many non-healing chronic wounds have been associated with chronic inflammation. A more detailed understanding of mechanisms controlling the inflammatory response and how inflammation directs the outcome of the healing process will provide therapeutics for tissue repair in chronic inflammatory diseases. The long-term goal of my research is to (1) understand the molecular and cellular mechanisms by which local inflammatory environmental cues alter phenotypic switch of tissue infiltrating innate immune cells and these cells functionally interact with mesenchymal stem cells, and (2) develop selective strategy to engineer microenvironmental cues towards tissue regeneration by utilizing micro/nano-engineered biomaterials that enable spatio-temporal control of inflammatory response. To achieve this goal, we combine interdisciplinary approaches of immuno-biology, stem cell biology, cellular and tissue engineering, and nano-bioengineering.

Publications

Kim MH, Gorouhi F, Ramirez S, Granick JL, Byrne BA, Soulika AM, Simon SI, Isseroff RR. Catecholamine stress alters neutrophil trafficking and impairs wound healing via beta 2 adrenergic receptor mediated upregulation of IL-6. Journal of Investigative Dermatology, In press, 2013

Kim MH, Yamayoshi I, Mathew S, Lin H, Nayfach J, and Simon SI, Magnetic nanoparticle targeted hyperthermia of cutaneous S. aureus infection. Annals of Biomedical Engineering, 41:598-609, 2013

Dixit N, Kim MH, Rossaint J, Yamayoshi I, Zarbock A, Simon SI, Leukocyte function antigen-1, kindlin-3, and calcium flux orchestrate neutrophil recruitment during Inflammation. J Immunology, 189:5954-5964, 2012

Kim MH, Granick J, Kwok C, Walker N, Borjesson DL, Curry F-E, Miller LS, and Simon SI. Neutrophil survival and c-kit+ progenitor proliferation in Stappylococcus aureus infected skin wounds promote resolution. Blood, 117(12):3343-3352, 2011

Simon SI and Kim MH, A day (or 5) in a neutrophil’s life. Blood, 116:511-512, 2010

Kim MH, Curry F-E, and Simon SI. Dynamics of neutrophil extravasation and vascular permeability are uncoupled during aseptic cutaneous wounding. American Journal of Physiology-Cell Physiology, 296: C848-C856, 2009

Kim MH, Liu W, Borjesson DL, Curry F-E, Miller LS, Cheung AL, Liu F-T, Isseroff RR, and Simon SI. Dynamics of neutrophil infiltration during cutaneous wound healing and infection using fluorescence imaging. Journal of Investigative Dermatology. 128: 1812-1820, 2008

Kim MH, Granger DN, and Harris NR. Mediators of CD18/P-selectin-dependent constriction of venule-paired arterioles in hypercholesterolemia. Microvascular Research, 73, pp. 150-155, 2007

Kim MH, Carter P, and Harris NR. P-selectin-mediated adhesion impairs endothelium-dependent arteriolar dilation in hypercholesterolemic mice. American Journal of Physiology -Heart and Circ Physiology. 292: H632-H638, 2007

Kim MH and Harris NR. Leukocyte adherence inhibits adenosine-dependent venular control of arteriolar diameter and nitric oxide. American Journal of Physiology-Heart and Circ Physiology. 291: H724-H731, 2006

Kim MH, Harris NR and Tarbell JM. Regulation of hydraulic conductivity in response to sustained changes in pressure. American Journal of Physiology-Heart and Circ Physiology. 289: H2551-H2558, 2005

Kim MH, Harris NR and Tarbell JM. Regulation of capillary hydraulic conductivity in response to acute change in shear. American Journal of Physiology-Heart and Circ Physiology, 289: H2126-H2135, 2005

Kim MH, Harris NR and Tarbell JM. Control of the arteriolar myogenic response by transvascular fluid filtration. Microvascular Research, 68, pp. 30-37, 2004

Research Areas
  • Immunolgy
  • Wound healing
  • Tissue Engineering
  • Nanobioengineering
Affiliations

Member, Biomedical Engineering Society

Member, International Society for Stem Cells Research

 

 


Min-Ho Kim
OFFICE
Department of Biological Sciences
Cunningham Hall
CONTACT INFO
Phone: 330-672-1445
Fax: 330-672-2893
mkim15@kent.edu
COURSES TEACHING
Spring 2014
  • BSCI 40158 - 001 Molecular Biology
  • BSCI 40196 - 018 Individual Investigation
  • BSCI 40600 - 008 Writing In Biological Sciences
  • BSCI 50158 - 001 Molecular Biology
  • BSCI 50196 - 004 Individual Investigation
  • BSCI 70158 - 001 Molecular Biology
Fall 2014
  • BSCI 40195 - 013 St : Medical Biotechnology
  • BSCI 40600 - 001 Writing In Biological Sciences
  • BSCI 50195 - 023 St : Medical Biotechnology
  • BSCI 70195 - 024 St : Medical Biotechnology
EXPERTISE