Nanoparticles as New Generation MRI Contrast Agents
Abstract: This invention describes a new class of non-gadolinium and non-iron oxide based nanoparticles that can be used as MRI contrast agents for cellular imaging in clinical diagnosis and biomedical research applications. We have demonstrated that these new generation MRI contrast agents are highly effective, non-toxic, and appear to be internalized by cells. Their stability in strong acidic media makes them ideal candidates for oral delivery to the human body. The invention is not an incremental improvement on the efficacy of MRI contrast agents, but rather a potentially revolutionary platform technology.
MRI / diagnostic contrast agents
Non-toxic yet highly effective
Inventors: Dr. Songping D. Huang, Dr. Soumitra Basu, Dr. Anatoly Khitrin, Mohammadreza Shokouhimehr and Eric Scott Soehnlen
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