I direct the Psychopathology and Emotion Regulation Laboratory (PERL) and am a Co-Director of the Kent Electrophysiological Neuroscience Laboratory (KENL). My program of research adopts an affective science perspective to the study of generalized anxiety disorder (GAD) and major depressive disorder (MDD). Working at the interface of cognitive behavioral and emotion regulation approaches, we conduct survey, experimental, and treatment research to examine factors associated with MDD and GAD including metacognitive factors (e.g., explanatory flexibility, decentering) utilizing measures of peripheral psychophysiology as well as electrophysiological (EEG) and functional neuroimaging (fMRI) techniques. Another focus of our lab is the development of treatments informed by affective and contemplative neuroscience findings that incorporate mindfulness meditation and other practices derived from Buddhist mental training exercises into Western psychosocial treatments. Presently, I am PI of grant (1R01HL119977) entitled, "Mindfulness-Based Stress Reduction for High Blood Pressure: A Two-Site RCT" and Co-I of a grant (1P30NR015326) entitled, "SMART Center II: Brain-Behavior Connections in Self-Management Science"
Hoge, E.A., Bui, E., Goetter, E., Robinaugh, D.J., Ojserkis, R.A., Fresco, D.M., Simon, N. (2015). Change in Decentering Mediates Improvement in Anxiety in Mindfulness-Based Stress Reduction for Generalized Anxiety Disorder, Cognitive Therapy and Research, 39, 228-235. NIHMSID # 635177
Bernstein, A., Hadash, Y., Lichtash, Y., Tanay, G., *Shepherd, K., & Fresco, D. M. (in press). Decentering and Related Constructs: A Critical Review and Meta-Cognitive Processes Model. Perspectives on Psychological Science.
Mennin, D. S., Fresco, D. M., Ritter, M., & Heimberg, R. G., (in press). An Open Trial of Emotion Regulation Therapy For Generalized Anxiety Disorder with Co-Occurring depression. Depression and Anxiety.
Hughes, J. W., Fresco, D. M., Myerscough, R., van Dulmen, M., Carlson, L. E., & Josephson, R. (2013). Randomized Controlled Trial of Mindfulness-based Stress Reduction for Prehypertension. Psychosomatic Medicine, 75, 721-728.
Mennin, D. S., Ellard, K. K., Fresco, D. M., & Gross, J. J. (2013). Emphasizing commonalities of cognitive-behavioral therapies within a broadening field of intervention science. Behavior Therapy, 44, 234-248.
Fresco, D. M., Segal, Z. V., Buis, T., & Kennedy, S. (2007). Relationship of post treatment decentering and cognitive reactivity following an emotion evocation challenge to relapse of major depressive disorder. Journal of Consulting and Clinical Psychology, 75, 447-455.
Fresco, D. M., *Moore, M. T., van Dulmen, M., Segal, Z. V., Teasdale, J. D., Ma, D., & Williams, J. M. G. (2007). Initial psychometric properties of the Experiences Questionnaire: A self-report survey of decentering. Behavior Therapy, 38, 234-246.