
Aaron Jasnow
Biography
Dr. Jasnow is now at the University of South Carolina School of Medicine, Department of Pharmacology, Physiology & Neuroscience. His new email address is: aaron.jasnow@uscmed.sc.edu
Graduate Areas:
Does Dr. Jasnow plan to recruit a doctoral student for the next incoming class?
Specialty:
- Behavioral Neuroscience
- Molecular Biology/Neurophysiology
Research Interests:
The Jasnow lab focuses on discovering how environmental experience alters emotional learning, as well as the molecular and cellular mechanisms of fear learning. PTSD and other fear-related disorders are thought to result from an interaction of genetic and environmental factors that enhance the likelihood of a pathological stress response and fear memory following severe trauma. Thus, if we can understand how genetic factors and environmental experience interact to alter basic brain function and ultimately emotional behavior, we can understand how these psychiatric disorders arise and develop potential therapeutic interventions. We use virus-mediated genetic manipulation and transgenic mouse models to discover the basic underlying brain mechanisms regulating prolonged physiological and behavioral responses to traumatic experience.
Lab Site: Jasnow Lab Behavioral Neuroscience
Research Areas
- Behavioral Neuroscience
- Fear and anxiety, Emotion
- Molecular biology
Publications
- Lynch, J. L. III, *Dejanovic, D., *Winiecki, P., *Mulvany, J., *Ortiz, S., Riccio, D. C., & Jasnow, A. M. (2014). Activation of ERβ modulates fear generalization through and effect on fear memory retrieval. Hormones and Behaviors, 66(2), 421-429. Full Text
- Cullen, P. C., *Dulka, B. N., *Ortiz, S., Riccio, D. C., & Jasnow, A. M. (2014). GABA-mediated presynaptic inhibition is required for precision of long-term memory. Learning and Memory, 21(4), 180-184. Full Text
- Meduri, J. M., Farnbauch, L. A., & Jasnow, A. M. (2013). Paradoxical enhancement of fear expression and extinction deficits in mice resilient to social defeat. Behavioral Brain Research, 256C, 580-590. Full Text
- Lynch, J. L. III., *Cullen P. C., Jasnow, A. M., & Riccio, D. C. (2013). Sex differences in the generalization of fear as a function of retention intervals. Learning and Memory, 20(11), 628-632. Full Text
- Jasnow, A. M., Ehrlich, D. E., Choi, D. C., Dabrowska, J., Bowers, M. E., McCullough, K. M., Rainnie, D. G., & Ressler, K. J. (2013). Thy1-expressing neurons in the basolateral amygdala may mediate fear inhibition. The Journal of Neuroscience, 33(25), 10396-404. Full Text
- Jasnow, A. M., Cullen, P. C., & Riccio, D. C. (2012). Remembering another aspect of forgetting. Frontiers in Psychology, 3, 1-8. Full Text
- Ryan, S. J., Ehrlich, D. E., Jasnow, A. M., Daftary, S., Madsen, T. E., & Rainnie, D. G. (2012). Spike-timing precision and neuronal synchrony are enhanced by an interaction between synaptic inhibition and membrane oscillations in the amygdala. PLoS One, 7(4), e35320. Full Text
- Gerecke, K. M., Kishore, R., Jasnow, A. M., Quadros-Mennella, P., Parker, S., Kozub, F. J., Lambert, K. G., & Kinsley, C. H. (2012). Alterations of sex-typical microanatomy: prenatal stress modifies the structure of medial preoptic area neurons in rats. Developmental Psychobiology, 54(1), 16-27. Full Text
- Jasnow, A. M., Ressler, K. J., Hammack, S. E., Chhatwal, J. P., & Rainnie, D. G. (2009). Distinct subtypes of Cholecystokinin-containing interneurons of the basolateral amygdala identified using a CCK promoter-specific lentivirus. Journal of Neurophysiology, 101(3), 1494-506. Full Text
- Jasnow, A. M., Mong, J. A., Romeo, R. D., & Pfaff, D. W. (2007). Estrogenic regulation of gene and protein expression within amygdala of female mice. Endocrine, 32(3), 271-279. Full Text
Education
The Rockefeller University
Emory University School of Medicine