Joe Bedont

I am a neuroscientist who studies how sleep and circadian rhythms interface with metabolism, prominently including autophagy and nitrogen homeostasis. My laboratory combines behavioral, imaging, and biochemical approaches in fruit fly and mouse models to study these interactions in both health and disease. Physiologically, we are interested in understanding how metabolism helps integrate competing needs of the organism, to prioritize behavioral outputs aimed at sating those needs. And pathologically, we are interested in how metabolism may connect deficient sleep and circadian disruption to various diseases, including neurodegenerative syndromes such as Alzheimer's disease, and chronic kidney disease.