NIH Grant Awarded for Multiple Sclerosis Research

Professors Jennifer McDonough (PI) and Ernie Freeman (PI) (Department of Biological Sciences) together with Professor Roger Gregory (co-PI) (Department of Chemistry and Biochemistry) have been awarded a two-year, $398,682 grant from the National Institutes of Health to support their project “Neuronal Expression of Hemoglobin in Multiple Sclerosis Cortex.”

Hemoglobin is a protein that transports oxygen in the blood, but surprisingly, it is also expressed by neurons and may be involved in neuronal respiration. Recent work by the research group at Kent found that hemoglobin expression is increased in multiple sclerosis brain tissue compared with controls [Broadwater et al, Biochimica et Biophysica Acta, 1812 (2011) 630–641]. The goal of this NIH funded research is to understand the regulation and function of hemoglobin expression in neurons, as well as the distribution and extent of hemoglobin expression in the brain and its significance to the neuropathology of multiple sclerosis.

  • Dr. Roger Gregory
    Dr. Roger Gregory
  • Hemoglobin
    Hemoglobin expression in multiple sclerosis postmortem brain tissue detected by immunofluorescent staining with antibodies to hemoglobin (red) and neurofilament (green).
POSTED: Saturday, September 29, 2012 04:34 PM
UPDATED: Saturday, December 03, 2022 01:02 AM

Kent State University faculty members have been contacted by various media outlets to lend their expert opinions and insight as cleanup work, air monitoring, water testing and more continues following the Feb. 3 train derailment in East Palestine, Ohio.

Western Reserve Historical Society and Kent State have announced a cooperation agreement enabling unique access and real-world experiences for students and faculty in the Department of History. Kent State students will gain access to archival research materials for research projects, internships and jobs as well as research assistantships for graduate level students.

David Kaplan, Ph.D., professor in the Department of Geography in the College of Arts and Sciences at Kent State University, was recently named a fellow of the American Association of Geographers (AAG) in recognition for his significant contributions to advancing geography.