Clinical Trials

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The KSUCPM Wound Care Research Clinic at the Cleveland Foot & Ankle Clinic is currently enrolling for Diabetic Foot Ulcers and Venous Leg Ulcers. Check back for more trials coming soon and sign up to be notified when relevant studies begin.


Clinical Trials Interest Form

These are wounds that often occur on the bottom aspect of foot, on top of toes or on the heel. Diabetic foot ulcers usually start as a thickened callus that develops with walking. Over time, the skin breaks down, leading to open sore formation.

Risk Factors for developing diabetic foot ulcers include:

  • Diabetes
  • Lack of sensation
  • Foot deformity
  • Arterial disease
  • Obesity
  • Smoking history
  • Poor Nutrition
  • Immobility

Venous leg ulcers are open sores that usually occur on the inside of the ankle region of the lower leg. VLUs seldom occur above the knee and are not typically seen on the foot or toes. These wounds can be painful and heavily draining. Often patients will also have a history of leg swelling, varicose veins or blood clots of the leg.

Risk Factors for developing venous leg ulcers include:

  • Obesity
  • High blood pressure
  • Heart failure
  • Previous leg surgeries
  • Blood clots of the leg
  • Kidney disease
  • Female gender
  • Pregnancy
  • Long hours standing
  • Immobility